Radiator — 16400-50280

OEM Part Number

16400-50280 — Radiator assembly, plastic top tank crimped onto aluminium core. Manufactured by Denso (OEM supplier to Toyota/Lexus). [Verified — Lexus parts catalogue]

What It Is

Main engine radiator for the 3UZ-FE 4.3L V8. Plastic/aluminium construction. The plastic top tank is the known failure point — see Radiator Plastic Tank Crack. Critical component — the 3UZ-FE is an all-aluminium engine and catastrophic damage can result from sudden overheating. [Probable — multiple forum reports]

Fitment

All SC430 (UZZ40) 2002–2010 with 3UZ-FE 4.3L V8. [Verified]

Aftermarket Alternatives

BrandPart NumberTypePrice (USD)Notes
Denso221-3175OEM-spec~$115-150Best option. Denso is the OEM manufacturer — this is effectively the same radiator without the Lexus box. ClubLexus owners report 6+ years no issues. [Probable — multiple forum reports]
Koyo / KoyoRadA2419OEM-spec~$166Koyo is OEM supplier for many Japanese makes. Reported as perfect fit on SC430. Well-regarded. [Probable — ClubLexus reports]
CSFHigh-performance~$250+High-end aftermarket. Full aluminium construction. Overkill for street use but excellent quality. [Reported]

Avoid

BrandWhy
TYCBudget tier. Plastic tank quality inconsistent. [Reported — forum consensus]
APDIBudget tier. Fit and finish issues reported. [Reported]
OSCBudget tier. [Reported]
Unbranded eBay/ChineseUnknown plastic tank quality — defeats the purpose of replacing a failed cheap radiator with another cheap radiator. [Probable — Leif’s mechanic suspects current radiator may be one of these]

Where to Buy (Australia)

  • Denso Australia — denso.com.au, or through Bursons/Repco trade accounts
  • eBay Australia — search “Denso 221-3175” or “SC430 radiator Denso”
  • Sparesbox — sparesbox.com.au, stocks Denso
  • Amayama — amayama.com, genuine Japanese parts, ships to AU
  • Amazon AU — check availability of Denso 221-3175

Pricing as at April 2026. Ask mechanic to check Bursons/Repco trade pricing first.

Installation Notes

  • Relatively straightforward job — ClubLexus owners report completing it in an afternoon [Probable]
  • Replacement radiators don’t include factory foam sealing/padding. Owners reuse old foam or use self-adhesive tape. One owner tested without foam — no temperature difference [Reported — single test]
  • Refill with Toyota Super Long Life Coolant (pink)
  • Bleed cooling system thoroughly after install

Sources

  • ClubLexus SC430 radiator replacement thread (2026-04-14 research)